Macrophage Cell Membrane Camouflaged Mesoporous Silica Nanocapsules for In Vivo Cancer Therapy

• DOI: 10.1002/adhm.201500129
• Publication Date: 2015-05-08T19:36:17Z
• Authors: Minjun Xuan; Jingxin Shao; Luru Dai; Qiang He; Junbai Li
• Keywords: Male; Drug Carriers; Mice, Inbred BALB C; Antibiotics, Antineoplastic; Cell Survival; Macrophages; Mice, Nude; 02 engineering and technology; Silicon Dioxide; 3. Good health; Mice; Nanocapsules; Phagocytosis; Doxorubicin; Cell Line, Tumor; Neoplasms; Animals; Transplantation, Homologous; Tissue Distribution; 0210 nano-technology; Porosity

Engineering natural macrophage cell membrane-camouflaged mesoporous silica nanocapsules can reduce the arrested percentage of immune cells and tissues, effectively prolong the survival time of nanoparticles in blood circulation system, and improve the accumulation in tumor.