Magnetically Actuated SiCN‐Based Ceramic Microrobot for Guided Cell Delivery

• DOI: 10.1002/adhm.201900739
• Publication Date: 2019-10-09T13:20:06Z
• Authors: Ki‐Won Gyak; Sungwoong Jeon; Laura Ha; Sangwon Kim; Jin‐young Kim; Kwang‐Sup Lee; Hongsoo Choi; Dong‐Pyo Kim
• Keywords: Inert; Biocompatible material

Abstract A silicon carbonitride (SICN) ceramic microrobot, biocompatible and magnetically activable, is developed for the delivery of viable cells to defective tissue by sequential steps microstructuring, magnetization, cell loading. The carrier porous cylindrical framework fabricated 3D laser lithography using a photocurable preceramic polymer, chemically modified polyvinylsilazane, subsequent pyrolysis at 600 °C under an inert atmosphere. Magnetic nanoparticles (MNP) are integrated into surface‐modified thiol‐ene click reaction. Finally, microrobot loaded with fibroblast cells, which can be guided rotating external magnetic field. proposed mechanically durable, adequately controllable field, quite compatible mammalian cells.