Hollow‐Structured Nanorobot with Excellent Magnetic Propulsion for Catalytic Pollutant Degradation, Anti‐Bacterial and Biofilm Removal

• DOI: 10.1002/adhm.202404208
• Publication Date: 2025-03-11T22:46:20Z
• Authors: Jing Wang; Guangjin Yu; Qunling Fang; Yunqi Xu; Jie Zhang; Ailing Hui; Shouhu Xuan; Ken Cham‐Fai Leung
• Keywords: Degradation

Abstract Chemical pollution, pathogenic bacteria, and bacterial biofilms pose significant threats to public health. Although various nanoplatforms with both catalytic antibacterial activities have been developed, creating a remotely controllable nanorobot precise targeting propulsion capabilities remains challenge. This study presents the fabrication of hollow‐structured Fe 3 O 4 @AgAu@polydopamine (PDA) nanosphere, which demonstrated activity superior magnetically enhanced biofilm removal properties. The AgAu bimetallic nanorods are assembled between core biocompatible PDA, resulting in magnetic high photothermal conversion efficiency (54%) excellent activity. Importantly, due efficient behavior originating from , organic pollutants such as 4‐nitrophenol methylene blue can be accurately degraded by @AgAu@PDA nanorobots simulated wastewater pool. By incorporating zinc phthalocyanine (ZnPc) photosensitizer, @AgAu@PDA‐ZnPc nanosphere exhibits synergistic “photothermal‐photodynamic‐Ag + ” effect against Escherichia coli Staphylococcus aureus . Remarkably, rate 99.99% applying via rotating field (RMF). Furthermore, this unique endows effective flat surfaces tubular structures, highlighting its advantages over traditional agents dynamic applications.