Near‐Infrared Light‐Triggered, Targeted Drug Delivery to Cancer Cells by Aptamer Gated Nanovehicles

• DOI: 10.1002/adma.201104797
• Publication Date: 2012-04-27T07:53:53Z
• Authors: Xinjian Yang; Xia Liu; Zhen Liu; Fang Pu; Jinsong Ren; Xiaogang Qu
• Keywords: Aptamer; Nanocarriers; Targeted drug delivery

A novel cell-targeting, near-infrared light-responsive drug delivery platform based on mesoporous silica-coated gold nanorods that are surface-functionalized with aptamer DNA is constructed. Aptamer used as both capping and targeting agent. In vitro studies show the feasibility of using this nanocarrier for targeted noninvasive remote controlled photothermal therapy. Detailed facts importance to specialist readers published "Supporting Information". Such documents peer-reviewed, but not copy-edited or typeset. They made available submitted by authors. Please note: The publisher responsible content functionality any supporting information supplied Any queries (other than missing content) should be directed corresponding author article.