DNA Patchy Particles

• DOI: 10.1002/adma.201204864
• Publication Date: 2013-04-03T08:27:02Z
• Authors: Lang Feng; Rémi Dreyfus; Ruojie Sha; Nadrian C. Seeman; Paul M. Chaikin
• Keywords: Streptavidin; DNA origami; Colloidal particle

A simple and effective way to make DNA patchy particles is reported. small patch of strands "stamped" from a gold surface onto colloidal different sizes by streptavidin-biotin bonds. These provide direction-selective thermoreversible interactions, hence can lead unique assembly protocols structures controlled temperature.