Periosteum‐Mimetic Structures Made from Freestanding Microgrooved Nanosheets

• DOI: 10.1002/adma.201305804
• Publication Date: 2014-03-11T07:24:44Z
• Authors: Xuetao Shi; Toshinori Fujie; Akihiro Saito; Shinji Takeoka; Ying Hou; Yiwei Shu; Mingwei Chen; Hongkai Wu; Ali Khademhosseini
• Keywords: Micropatterning; Nanosheet; Periosteum; PLGA

A "sticker-like" PLGA nanosheet with microgrooved patterns is developed through a facile combination of spin coating and micropatterning techniques. The resulting nanosheets can be physically adhered on flat or porous surfaces excellent stability in aqueous environments harness the spatial arrangements cells, which make it promising candidate for generating biomimic periosteum bone regenerative applications.