Periosteum‐Mimetic Structures Made from Freestanding Microgrooved Nanosheets
0301 basic medicine
adhesiveness
02 engineering and technology
micropattern
nanosheet
Bone and Bones
03 medical and health sciences
Polylactic Acid-Polyglycolic Acid Copolymer
Biomimetic Materials
Osteogenesis
Periosteum
Cell Adhesion
Animals
Humans
Lactic Acid
Cells, Cultured
Tissue Scaffolds
periosteum
Water
Mesenchymal Stem Cells
bone repair
Nanostructures
3. Good health
Microscopy, Electron, Scanning
0210 nano-technology
Chickens
Porosity
Polyglycolic Acid
DOI:
10.1002/adma.201305804
Publication Date:
2014-03-11T07:24:44Z
AUTHORS (9)
ABSTRACT
A "sticker-like" PLGA nanosheet with microgrooved patterns is developed through a facile combination of spin coating and micropatterning techniques. The resulting microgrooved PLGA nanosheets can be physically adhered on flat or porous surfaces with excellent stability in aqueous environments and can harness the spatial arrangements of cells, which make it a promising candidate for generating biomimic periosteum for bone regenerative applications.
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