Integrating Oxaliplatin with Highly Luminescent Carbon Dots: An Unprecedented Theranostic Agent for Personalized Medicine
Organoplatinum Compounds
Cell Survival
Carbon Compounds, Inorganic
Optical Imaging
Antineoplastic Agents
Hep G2 Cells
02 engineering and technology
Fibroblasts
Fluorescence
Cell Line
3. Good health
Oxaliplatin
Mice
Nanomedicine
Cell Line, Tumor
Quantum Dots
Animals
Humans
Drug Monitoring
Particle Size
Precision Medicine
0210 nano-technology
HeLa Cells
DOI:
10.1002/adma.201306192
Publication Date:
2014-03-14T16:56:28Z
AUTHORS (10)
ABSTRACT
A theranostic nanomedicine (CD-Oxa) is synthesized by means of the condensation reaction between the amino groups on the surface of fluorescent carbon dots (CDs) and the carboxyl group of the oxaliplatin derivative Oxa(IV)-COOH. CD-Oxa, which integrates the optical properties of CDs and the anticancer function of oxaliplatin, could be used for simultaneous drug delivery and fluorescent tracking.
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