Integrating Oxaliplatin with Highly Luminescent Carbon Dots: An Unprecedented Theranostic Agent for Personalized Medicine

Organoplatinum Compounds Cell Survival Carbon Compounds, Inorganic Optical Imaging Antineoplastic Agents Hep G2 Cells 02 engineering and technology Fibroblasts Fluorescence Cell Line 3. Good health Oxaliplatin Mice Nanomedicine Cell Line, Tumor Quantum Dots Animals Humans Drug Monitoring Particle Size Precision Medicine 0210 nano-technology HeLa Cells
DOI: 10.1002/adma.201306192 Publication Date: 2014-03-14T16:56:28Z
ABSTRACT
A theranostic nanomedicine (CD-Oxa) is synthesized by means of the condensation reaction between the amino groups on the surface of fluorescent carbon dots (CDs) and the carboxyl group of the oxaliplatin derivative Oxa(IV)-COOH. CD-Oxa, which integrates the optical properties of CDs and the anticancer function of oxaliplatin, could be used for simultaneous drug delivery and fluorescent tracking.
SUPPLEMENTAL MATERIAL
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