A Novel Magnetic Hydrogel with Aligned Magnetic Colloidal Assemblies Showing Controllable Enhancement of Magnetothermal Effect in the Presence of Alternating Magnetic Field

• DOI: 10.1002/adma.201405757
• Publication Date: 2015-03-09T17:52:16Z
• Authors: Ke Hu; Jianfei Sun; Zhaobin Guo; Peng Wang; Qiang Chen; Ming Ma; Ning Gu
• Keywords: Drug Carriers; Magnetic Fields; Doxorubicin; Magnets; Temperature; Colloids; 02 engineering and technology; 0210 nano-technology; Hydrogel, Polyethylene Glycol Dimethacrylate

A novel magnetic hydrogel is formed via the field-directed assembly of magnetic nanomaterials during the gelation process. The novel magnetic hydrogel exhibits direction-dependent thermogenesis in an alternating magnetic field. The specific absorption rate value in the direction along the assemblies can be 2.1-fold as much as that in the direction normal to the assemblies while the heating rate is 6-8-fold. Due to the anisotropic thermogenesis, the novel magnetic hydrogel also shows a direction-dependent release of drugs that has a 3.4-fold difference between the two directions.