Smart Albumin‐Biomineralized Nanocomposites for Multimodal Imaging and Photothermal Tumor Ablation

• DOI: 10.1002/adma.201500229
• Publication Date: 2015-05-21T17:33:01Z
• Authors: Yong Wang; Tao Yang; Hengte Ke; Aijun Zhu; Yangyun Wang; Junxin Wang; Junkang Shen; Gang Liu; Chunying Chen; Yuliang Zhao; Huabing Chen
• Keywords: Ablation Techniques; Models, Molecular; Minerals; Indoles; Protein Conformation; Mammary Neoplasms, Experimental; Gadolinium; Serum Albumin, Bovine; 02 engineering and technology; Hydrogen-Ion Concentration; Phototherapy; Multimodal Imaging; Theranostic Nanomedicine; Nanocomposites; Mice; Cell Line, Tumor; Animals; Nanoparticles; Cattle; Propionates; 0210 nano-technology

Smart cyanine-grafted gadolinium oxide nanocrystals (Cy-GdNCs) obtained by albumin-based biomineralization are shown to be theranostic nanocomposites, with promising properties for trimodal near-infrared fluorescence/photoacoustics/magnetic-resonance imaging-guided photothermal tumor ablation.