Deep Photoacoustic/Luminescence/Magnetic Resonance Multimodal Imaging in Living Subjects Using High‐Efficiency Upconversion Nanocomposites

• DOI: 10.1002/adma.201506460
• Publication Date: 2016-05-17T06:56:36Z
• Authors: Yu Liu; Ning Kang; Jing Lv; Zijian Zhou; Qingliang Zhao; Lingceng Ma; Zhong Chen; Lei Ren; Liming Nie
• Keywords: Photon Upconversion

A gadolinium-doped multi-shell upconversion nanoparticle under 800 nm excitation is synthesized with a 10-fold fluorescence-intensity enhancement over that 980 nm. The nanoformulations exhibit excellent photoacoustic/luminescence/magnetic resonance tri-modal imaging capabilities, enabling visualization of tumor morphology and microvessel distribution at new depth. As service to our authors readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed may be re-organized for online delivery, but not copy-edited or typeset. Technical support issues arising from (other than missing files) should addressed Please note: publisher responsible content functionality any Any queries content) directed corresponding author article.