Near‐Infrared Upconversion Chemodosimeter for In Vivo Detection of Cu2+ in Wilson Disease

• DOI: 10.1002/adma.201601140
• Publication Date: 2016-05-17T06:43:34Z
• Authors: Yi Liu; Qianqian Su; Min Chen; Yi Dong; Yibing Shi; Wei Feng; Zhi‐Ying Wu; Fuyou Li
• Keywords: Hepatolenticular Degeneration; Cations, Divalent; Humans; 01 natural sciences; Copper; 0104 chemical sciences; 3. Good health

Near-infrared upconversion chemodosimetry is a promising detection method by virtue of the frequency upconversion technique, which shows very high sensitivity and selectivity for the detection of Cu(2+) ions in vitro and in vivo. This method offers a new opportunity for noninvasive diagnosis of Wilson disease associated with Cu(2+) detection in clinical medicine.