Activatable Photoacoustic Nanoprobes for In Vivo Ratiometric Imaging of Peroxynitrite

• DOI: 10.1002/adma.201604764
• Publication Date: 2016-12-01T15:08:04Z
• Authors: Jianjian Zhang; Xu Zhen; Paul Kumar Upputuri; Manojit Pramanik; Peng Chen; Kanyi Pu
• Keywords: Boranes

Organic semiconducting nanoprobes doped with bulky borane can undergo specific activation by ONOO- even at tumor-relevant acidic pH (6.8), permitting in vivo ratiometric photoacoustic imaging of the tumor environment living mice.