Tensile‐Strained Palladium Nanosheets for Synthetic Catalytic Therapy and Phototherapy

• DOI: 10.1002/adma.202202609
• Publication Date: 2022-05-25T04:39:21Z
• Authors: Shanshan Li; Bolong Xu; Mingzhu Lu; Mengxue Sun; Haokun Yang; Shuang Liu; Zhijun Huang; Huiyu Liu
• Keywords: Nanomaterials; Inert

Palladium nanosheets (Pd NSs) are well-investigated photothermal therapy agents, but their catalytic potential for tumor has been underexplored owing to the inactive dominant (111) facets. Herein, lattice tensile strain is introduced by surface reconstruction activate inert surface, endowing strained Pd NSs (SPd with photodynamic, catalase-like, and peroxidase-like properties. Tensile promoting photodynamic enzyme-like activities revealed density functional theory calculations. Compared NSs, SPd exhibit lower effect, approximately five times higher inhibition rate. This work calls further study nanomaterials engineering of tumors.