Multifunctional Biomimetic Nanovaccines Based on Photothermal and Weak‐Immunostimulatory Nanoparticulate Cores for the Immunotherapy of Solid Tumors (Adv. Mater. 9/2022)

• DOI: 10.1002/adma.202270074
• Publication Date: 2022-03-03T08:49:43Z
• Authors: Jiachen Li; Di Huang; Ruoyu Cheng; Patrícia Figueiredo; Flavia Fontana; Alexandra Correia; Shiqi Wang; Zehua Liu; Marianna Kemell; Giulia Torrieri; Ermei M. Mäkilä; Jarno J. Salonen; Jouni Hirvonen; Yan Gao; Jialiang Li; Zhenyang Luo; Hélder A. Santos; Bing Xia
• Keywords: Porous Silicon; Cancer Immunotherapy

Nanovaccines A cancer cell membrane@porous silicon nanoparticles@Au nanovaccine is developed by Zhenyang Luo, Hélder A. Santos, Bing Xia, and co-workers in article number 2108012, based on weak-immunostimulatory porous silicon@Au nanoparticulate cores multi-antigenic membranes. These exogenous nanovaccines boost antitumor immunity, preventing the occurrence of solid tumors, significantly inhibiting growth metastasis tumors after photothermal therapy combined with immune checkpoint inhibitors.