Interface‐Stabilized Fiber Sensor for Real‐Time Monitoring of Amniotic Fluid During Pregnancy

• DOI: 10.1002/adma.202307726
• Publication Date: 2023-09-30T00:14:00Z
• Authors: Qianming Li; Dan Li; Jiang Lu; Kuangyi Zou; Lie Wang; Yiding Jiao; Maosen Wang; Rui Gao; Jie Song; Yiran Li; Fangyan Li; Jianjian Ji; Jiacheng Wang; Luhe Li; Tingting Ye; Er He; Hao Chen; Yuanzhen Wang; Junye Ren; Chenyu Bai; Shuo Yang; Ye Zhang
• Keywords: Amnion; Hypoxia

Diseases in pregnancy endanger millions of fetuses worldwide every year. The onset these diseases can be early warned by the dynamic abnormalities biochemicals amniotic fluid, thus requiring real-time monitoring. However, when continuously penetrated detection devices, amnion is prone to loss robustness and rupture, which difficult regenerate. Here, an interface-stabilized fiber sensor presented for monitoring biochemical dynamics fluid during pregnancy. seamlessly integrated into through tissue adhesion, regeneration, uniform stress distribution, posing no risk environment. demonstrates a response performance less than 0.3% fluctuation under complex conditions accuracy more 98% from second third trimester. By applying it warning such as intrauterine hypoxia, infection, fetal growth restriction, survival increases 95% with timely intervention.