Sensing, Imaging, and Therapeutic Strategies Endowing by Conjugate Polymers for Precision Medicine

• DOI: 10.1002/adma.202310032
• Publication Date: 2024-02-07T08:46:08Z
• Authors: Qi Shen; Gang Song; Hongrui Lin; Haotian Bai; Yiming Huang; Fengting Lv; Shu Wang
• Keywords: Conjugate

Abstract Conjugated polymers (CPs) have promising applications in biomedical fields, such as disease monitoring, real‐time imaging diagnosis, and treatment. As a luminescent material with tunable emission, high brightness excellent stability, CPs are widely used fluorescent probes biological detection imaging. Rational molecular design structural optimization broadened absorption/emission range of CPs, which more conductive for diagnosis precision therapy. This review provides comprehensive overview recent advances the application aiming to elucidate their functional relationships. The fluorescence properties mechanism signal amplification first discussed, followed by an elucidation emerging detection. Subsequently, CPs‐based systems therapeutic strategies illustrated systematically. Finally, advancements utilizing electroactive materials bioelectronic devices also investigated. Moreover, challenges outlooks medicine discussed. Through this systematic review, it is hoped highlight frontier progress promote new breakthroughs fundamental research clinical transformation.