Plant‐Based Shape Memory Cryogel for Hemorrhage Control

• DOI: 10.1002/adma.202311684
• Publication Date: 2024-07-16T09:37:51Z
• Authors: J. Deng; Z. Zhao; X.Y. Yeo; C. Yang; J. Yang; A.R. Ferhan; B. Jin; C. Oh; S. Jung; S. Suresh; N.‐J. Cho
• Keywords: Penetration (warfare)

The escalating global demand for sustainable manufacturing, motivated by concerns over energy conservation and carbon footprints, encounters challenges due to insufficient renewable materials arduous fabrication procedures fulfill specific requirements in medical healthcare systems. Here, biosafe pollen cryogel is engineered as effective hemostats without additional harmful crosslinkers treat deep noncompressible wounds. A straightforward low-energy approach involved forming stable macroporous cryogel, benefiting from the unique micro-hierarchical structures chemical components of non-allergenic plant pollen. It demonstrated that exhibits rapid water/blood-triggered shape-memory properties within 2 s. Owing their inherent nano/micro hierarchical structure abundant functional groups on surface, shows hemostatic performance a mouse liver penetration model, which easily removed after usage. Overall, self-crosslinking this work pioneers framework potential clinical applications first-hand treatment