Iridium‐Catalyzed Asymmetric Hydrogenation of Vinyl Ethers

• DOI: 10.1002/adsc.200700546
• Publication Date: 2008-03-07T14:47:54Z
• Authors: Ye Zhu; Kevin Burgess
• Keywords: 01 natural sciences; 0104 chemical sciences

AbstractA carbene‐oxazoline catalyst 1 proved to be an effective catalyst for reduction of an enol ether that the literature suggested could not be hydrogenated effectively by P,N‐Ir catalysts. Thus, a series of ester and alcohol substrates were hydrogenated using catalyst 1. Good to excellent enantioselectivities and high conversions were obtained.