Copper‐Catalyzed One‐Pot Approach to α‐Aryl Amidines via Truce‐Smiles Rearrangement

• DOI: 10.1002/adsc.201800490
• Publication Date: 2018-06-15T01:59:30Z
• Authors: Ying Huang; Weiyin Yi; Qihui Sun; Fengping Yi
• Keywords: Smiles Rearrangement; Stoichiometry; Sulfonyl

Abstract A copper‐catalyzed one‐pot approach to α‐aryl amidines from terminal alkynes, sulfonyl azides, and aryl sulfonamides via a Truce‐Smiles rearrangement under mild condition in good excellent yields was reported for the first time. The formation of such aryl‐ sp 3 C−C bond previously could not be directly achieved by common method. stoichiometry substrates played an important role improving desired products. In addition, two sets signals were observed 1 H NMR spectra their possible cause investigated control experiments as well. magnified image