Delivery of Dissociated Islets Cells within Microporous Annealed Particle Scaffold to Treat Type 1 Diabetes

• DOI: 10.1002/adtp.202200064
• Publication Date: 2022-07-02T07:23:12Z
• Authors: Colleen A. Roosa; Mingyang Ma; Preeti Chhabra; Kenneth Brayman; Donald Griffin
• Keywords: Pancreatic Islets

Type 1 diabetes (T1D) is caused by the autoimmune loss of insulin-producing beta cells in pancreas. The only clinical approach to patient management blood glucose that doesn't require exogenous insulin pancreas or islet transplantation. Unfortunately, donor islets are scarce and there substantial immediately after transplantation due, part, local inflammatory response. delivery stem cell-derived (