Tissue Expansion: Scalable and Isotropic Expansion of Tissues with Simply Tunable Expansion Ratio (Adv. Sci. 22/2019)

• DOI: 10.1002/advs.201970131
• Publication Date: 2019-11-20T10:12:03Z
• Authors: Han‐Eol Park; Dongkil Choi; Ji Su Park; Changgon Sim; Sohyun Park; Sunah Kang; Hyunsoo Yim; Myungsun Lee; Jaeyoun Kim; Jinyoung Pac; Kunsoo Rhee; Junho Lee; Yunjong Lee; Yan Lee; Sung‐Yon Kim
• Keywords: Cover Picture; 01 natural sciences; 0104 chemical sciences

In article number https://doi.org/10.1002/advs.201901673, Yan Lee, Sung‐Yon Kim, and co‐workers develop ZOOM, a new tissue expansion technique based on the hydrogel conversion reaction, to enable scalable and isotropic expansion of biological samples with easily tunable expansion ratio (up to eightfold). This method allows for simple and flexible expansion of a wide range of biological samples, from bacteria to human brain tissues, for super‐resolution imaging of samples with ordinary microscopes. [Image: see text]