Ultra‐Conformable Ionic Skin with Multi‐Modal Sensing, Broad‐Spectrum Antimicrobial and Regenerative Capabilities for Smart and Expedited Wound Care

• DOI: 10.1002/advs.202004627
• Publication Date: 2021-02-18T19:28:20Z
• Authors: Xiao Lin; Yuxuan Mao; Peng Li; Yanjie Bai; Tao Chen; Kang Wu; Dandan Chen; Huilin Yang; Lei Yang
• Keywords: Conformable matrix; Wound care; Broad spectrum; Human skin

Abstract While rapid wound healing is essential yet challenging, there also an unmet need for functional restoration of sensation. Inspired by natural skin, ultra‐conformable, adhesive multi‐functional ionic skin (MiS) with multi‐modal sensing capability devised smart and expedited care. The base MiS a unique skin‐like, conductive self‐adaptive polyacrylamide/starch double‐network hydrogel (PSH) self‐powered, flexible, triboelectric sensor(s) integrated on top PSH multi‐tactile sensing. could enhance contraction, collagen deposition, angiogenesis, epidermis formation in full‐thickness defect model vivo , while significantly inhibiting the biofilm wide range microorganisms. exhibits instant therapeutics diagnostics, including displacement or joint motion, temperature, pressure tissue exudate changes bed, locally releasing drugs pH‐responsive manner. More importantly, restore skin‐mimicking tactile function both touch location intensity, thus be used as human‐machine interface accurate external robotic control. demonstrates new comprehensive paradigm combining diagnosis healing, broad‐spectrum anti‐microbial reparation severe wound.