GhMPK9‐GhRAF39_1‐GhWRKY40a Regulates the GhERF1b‐ and GhABF2‐Mediated Pathways to Increase Cotton Disease Resistance

• DOI: 10.1002/advs.202404400
• Publication Date: 2024-06-07T05:39:46Z
• Authors: Xinyue Mi; Weixi Li; Chuan Chen; Huijuan Xu; Guilin Wang; Xuanxiang Jin; Dayong Zhang; Wangzhen Guo
• Keywords: WRKY protein domain; Verticillium dahliae; Verticillium wilt; Verticillium; MAPK cascade

Abstract Mitogen‐activated protein kinase (MAPK) cascade is the center of plant signal transduction system that amplify immune signals into cellular responses by phosphorylating diverse substrates. The MAPK consisting kinases (MAPKKKs), (MAPKKs), and MAPKs well characterized in plants, which Raf‐like are generally regarded as MAPKKKs. However, it rarely reported MAPKKKs function middle regulators to link its downstream transcription factors immunity. Verticillium wilt, caused soil‐borne vascular fungus dahliae , a serious disease many including cotton. previous studies showed GhMPK9 (a MAPK) involved response wilt. Here, GhRAF39_1 helper regulates phosphorylation WRKY factor GhWRKY40a GhMPK9. phosphorylated can further activate GhERF1b up‐regulate defense‐related genes while inhibit GhABF2 regulate stomatal opening, thus improving resistance wilt This study reveals new signaling module GhMPK9‐GhRAF39_1‐GhWRKY40a ‐ ‐mediated defense responses, triggers against