Robotic Laser Tissue Soldering for Atraumatic Soft Tissue Fusion Guided by Fluorescent Nanothermometry

• DOI: 10.1002/advs.202406671
• Publication Date: 2024-11-21T11:34:44Z
• Authors: Oscar Cipolato; Tobias Leuthold; Marius Zäch; Georg Männel; Sam Aegerter; Calinda Sciascia; Alexander Jessernig; Marco von Salis; Sima Sarcevic; Jachym Rosendorf; Vaclav Liska; Dennis Kundrat; Romain Quidant; Inge K. Herrmann
• Keywords: Invasive surgery; Biological tissue

Abstract Minimally invasive surgical techniques, including endoscopic and robotic procedures, continue to revolutionize patient care, for their ability minimize trauma, thus promoting faster recovery reduced hospital stays. Yet, the suturing of soft tissues ensuring damage‐free tissue bonding during these procedures remains challenging due missing haptics fulcrum effect. Laser soldering has potential in overcoming issues, offering atraumatic seamless fusion. To ensure precision safety laser soldering, study introduces feedback‐controlled fluorescent nanothermometry‐guided using nanoparticle‐protein solders within contexts. Temperature‐sensitive nanoparticles embedded solder provide surgeons with immediate feedback on temperatures application, all while confines minimally (robotic) setups. By integrating surgery into surgery, paves way a new approach safe joining, especially regions where traditional is unfeasible.