The Matrix Protein Tropoelastin Prolongs Mesenchymal Stromal Cell Vitality and Delays Senescence During Replicative Aging (Adv. Sci. 39/2024)

• DOI: 10.1002/advs.202470235
• Publication Date: 2024-10-23T09:54:41Z
• Authors: Sunny Shinchen Lee; Aleen Al Halawani; Jonathan D. Teo; Anthony S. Weiss; Giselle C. Yeo
• Keywords: Senescence; Tropoelastin; Vitality; Matrix (chemical analysis)

Mesenchymal Stromal Cells The hourglass represents the passage of time, which leads to the inevitable aging of the entrapped mesenchymal stromal cells. The matrix protein, tropoelastin, depicted as the purple molecule, exerts strong influence over cellular aging, by delaying age‐related dysfunction and preserving youth‐associated traits. More details can be found in article number 2402168 by Anthony S. Weiss, Giselle C. Yeo, and co‐workers. [Image: see text]