The effects of 2100‐MHz radiofrequency radiation on nasal mucosa and mucociliary clearance in rats

• DOI: 10.1002/alr.21509
• Publication Date: 2015-04-16T10:35:55Z
• Authors: Filiz Aydoğan; Emine Aydın; Gökhan Koca; Elçin Özgür; Pergin Atilla; Arzu Tüzüner; Şule Demirci; Arin Tomruk; Göknur Güler Öztürk; Nesrin Seyhan; Meliha Korkmaz; Sevda Müftüoğlu; Ethem Erdal Samim
• Keywords: Mucociliary clearance

Background Nasal mucociliary clearance has an important role in voiding the airways from inhaled foreign substances. This activity could be disturbed by environmental factors such as radiofrequency radiation. The aim of present study was to investigate short‐term and relatively long‐term effects 2100‐MHz radiation emitted a generator, simulating 3G‐mobile phone, on nasal septal mucosa rats. Methods Thirty Wistar albino rats were divided into 4 groups. There 6 Group A B, which served control groups (10‐day 40‐day groups, respectively). Groups C exposure) D (40‐day both composed 9 rats; they comprised exposure exposed hours/day, for 10 or 40 days, respectively. After exposure, measured rhinoscintigraphy. euthanization, septa animals removed, tissue samples examined using transmission electron microscope. Results differences clearances between C, B D, found statistically significant ( p = 0.005, < 0.001, Although there no histopathological abnormalities showed number degenerated apoptotic cells, ciliary disorganization loss epithelial metaplasia, alteration normal chromatin distribution karyolysis nuclei, changes basal lymphocytic infiltration. more severe group D. Conclusion Radiofrequency at 2100 MHz damaged mucosa, clearance. Ciliary cells resulted deterioration