A Chiral Recognition System Orchestrated by Self‐Assembly: Molecular Chirality, Self‐Assembly Morphology, and Fluorescence Response

• DOI: 10.1002/ange.201706142
• Publication Date: 2017-07-27T13:58:47Z
• Authors: Takao Noguchi; Bappaditya Roy; Daisuke Yoshihara; Junji Sakamoto; Tatsuhiro Yamamoto; Seiji Shinkai
• Keywords: Chirality; Morphology

Abstract The newly developed oligophenylenevinylene (OPV)‐based fluorescent (FL) chiral chemosensor (OPV‐Me) for the representative enantiomeric guest, 1,2‐cyclohexanedicarboxylic acid (1,2‐CHDA: RR ‐ and SS ‐form) showed high discrimination ability, resulting in different aggregation modes of OPV‐Me self‐assembly: ‐CHDA directed fibrous supramolecular aggregate, whereas finite aggregate. consequent FL intensity toward was up to 30 times larger than that ‐CHDA. Accordingly, highly enantioselective recognition achieved. Application chirality sensing also possible: exhibited a linear relationship between excess through morphological development stereocomplex aggregates. These results clearly show ability is manifested by amplification cascade difference self‐assembly.