Enantioselective Intermolecular Heck and Reductive Heck Reactions of Aryl Triflates, Mesylates, and Tosylates Catalyzed by Nickel

• DOI: 10.1002/ange.202011036
• Publication Date: 2020-11-03T03:12:02Z
• Authors: Xiaolei Huang; Shenghan Teng; Yonggui Robin Chi; Wenqiang Xu; Maoping Pu; Yun‐Dong Wu; Jianrong Steve Zhou
• Keywords: Heck Reaction; Cyclopentenone; Conjugate; Enone

Abstract Nickel‐catalyzed intermolecular Heck reaction of cycloalkenes proceeds well with aryl triflates, mesylates and tosylates in excellent enantiomeric ratios. The asymmetric reductive also works a 2‐cyclopentenone ketal, which is equivalent to conjugate arylation the enone itself.