Starving the Malaria Parasite: Inhibitors Active against the Aspartic Proteases Plasmepsins I, II, and IV

• DOI: 10.1002/anie.200504119
• Publication Date: 2006-02-27T09:46:50Z
• Authors: Fraser Hof; Andri Schütz; Christoph Fäh; Solange Meyer; Daniel Bur; Jun Liu; Daniel E. Goldberg; François Diederich
• Keywords: Models, Molecular; Plasmodium; Binding Sites; Protozoan Proteins; Cathepsins; 01 natural sciences; Malaria; 0104 chemical sciences; Antimalarials; Structure-Activity Relationship; Models, Chemical; Animals; Aspartic Acid Endopeptidases; Humans; Protease Inhibitors; Protein Binding