End‐to‐End Continuous Manufacturing of Pharmaceuticals: Integrated Synthesis, Purification, and Final Dosage Formation

• DOI: 10.1002/anie.201305429
• Publication Date: 2013-10-04T09:45:29Z
• Authors: Salvatore Mascia; Patrick L. Heider; Haitao Zhang; Richard Lakerveld; Brahim Benyahia; Paul I. Barton; Richard D. Braatz; Charles L. Cooney; James M. B. Evans; Timothy F. Jamison; Klavs F. Jensen; Allan S. Myerson; Bernhardt L. Trout
• Keywords: Pharmaceutical Manufacturing

A series of tubes: The continuous manufacture a finished drug product starting from chemical intermediates is reported. pilot-scale plant used novel route that incorporated many advantages continuous-flow processes to produce active pharmaceutical ingredients and the in one integrated system. As service our authors readers, this journal provides supporting information supplied by authors. Such materials are peer reviewed may be re-organized for online delivery, but not copy-edited or typeset. Technical support issues arising (other than missing files) should addressed Please note: publisher responsible content functionality any Any queries content) directed corresponding author article.