Acetylcholinesterase‐Catalyzed Hydrolysis Allows Ultrasensitive Detection of Pathogens with the Naked Eye

• DOI: 10.1002/anie.201307952
• Publication Date: 2013-10-23T16:50:17Z
• Authors: Dingbin Liu; Zhantong Wang; Albert Jin; Xinglu Huang; Xiaolian Sun; Fu Wang; Qiang Yan; Shengxiang Ge; Ningshao Xia; Gang Niu; Gang Liu; A. R. Hight Walker; Xiaoyuan Chen
• Keywords: Naked eye

Seeing is believing: A rapid diagnostic platform for pathogen detection based on the acetylcholinesterase-catalyzed hydrolysis reaction has been developed. Owing to signal amplification strategies, sensitivity of this assay comparable that PCR. In addition, readout solution color change, which can be easily observed by naked eye alone. As a service our authors and readers, journal provides supporting information supplied authors. Such materials are peer reviewed may re-organized online delivery, but not copy-edited or typeset. Technical support issues arising from (other than missing files) should addressed Please note: The publisher responsible content functionality any Any queries content) directed corresponding author article.