Cobalt‐Catalyzed C(sp2)H Alkoxylation of Aromatic and Olefinic Carboxamides

• DOI: 10.1002/anie.201409751
• Publication Date: 2014-11-12T15:00:27Z
• Authors: Lin‐Bao Zhang; Xin‐Qi Hao; Shou‐Kun Zhang; Zhan‐Jiang Liu; Xin‐Xiang Zheng; Jun‐Fang Gong; Jun‐Long Niu; Mao‐Ping Song
• Keywords: Benzamide

Abstract The cobalt‐catalyzed alkoxylation of C(sp 2 )H bonds in aromatic and olefinic carboxamides has been developed. reaction proceeded under mild conditions the presence Co(OAc) ⋅4H O as catalyst tolerates a wide range both alcohols benzamide substrates, including even carboxamides. In addition, this is first example direct alkenes through CH bond activation.