A Single Fluorescent Probe to Visualize Hydrogen Sulfide and Hydrogen Polysulfides with Different Fluorescence Signals

• DOI: 10.1002/anie.201604892
• Publication Date: 2016-07-13T16:54:24Z
• Authors: Wei Chen; Armando Pacheco; Yoko Takano; Jacob J. Day; Kenjiro Hanaoka; Ming Xian
• Keywords: Rational design

Abstract Hydrogen sulfide (H 2 S) and hydrogen polysulfides S n , >1) are endogenous regulators of many physiological processes. In order to better understand the symbiotic relationship cellular cross‐talk between H it is highly desirable develop single fluorescent probes which enable dual‐channel discrimination . Herein, we report rational design, synthesis, evaluation first dual‐detection probe DDP‐1 that can visualize with different fluorescence signals. The showed high selectivity sensitivity in aqueous media cells.