Generating New Cross‐Relaxation Pathways by Coating Prussian Blue on NaNdF4 To Fabricate Enhanced Photothermal Agents

• DOI: 10.1002/anie.201904534
• Publication Date: 2019-04-15T11:48:07Z
• Authors: Zhongzheng Yu; Wenbo Hu; Hui Zhao; Xiaofei Miao; Yan Guan; Weizheng Cai; Zhiping Zeng; Quli Fan; Timothy Thatt Yan...
• Keywords: :Bioengineering [Engineering]; Dyes/Pigments; Cross-relaxation; 02 engineering and technology; 0210 nano-technology; 7. Clean energy

AbstractCross‐relaxation among sensitizers is commonly regarded as deleterious in fluorescent materials, although favorable in photothermal agents. Herein, we coated Prussian blue (PB) on NaNdF4 nanoparticles to fabricate core–shell nanocomplexes with new cross relaxation pathways between the ladder‐like energy levels of Nd3+ ions and continuous energy band of PB. The photothermal conversion efficiency was improved exceptionally and the mechanism of the enhanced photothermal effect was investigated. In vivo photoacoustic imaging and photothermal therapy demonstrated the potential of the enhanced photothermal agents. Moreover, the concept of generating new cross‐relaxation pathways between different materials is proposed to contribute to the design of all kinds of enhanced photothermal agents.