Enantioselective Tail‐to‐Head Terpene Cyclizations by Optically Active Hexameric Resorcin[4]arene Capsule Derivatives

• DOI: 10.1002/anie.202203384
• Publication Date: 2022-03-25T00:23:35Z
• Authors: Daria Sokolova; GiovanniMaria Pic...; Konrad Tiefenbacher
• Keywords: Terpene; Capsule

Molecular capsules enable the conversion of substrates inside a closed cavity, mimicking to some extent enzymatic catalysis. Chirality transfer from molecular capsule onto encapsulated substrate has been only studied in few cases. Here we demonstrate that chirality is possible rather large container approximately 1400 Å