Antibacterial oil‐based polyurethane films for wound dressing applications

• DOI: 10.1002/app.30788
• Publication Date: 2009-10-07T16:21:22Z
• Authors: Ferhat Yücedag; Cigdem Atalay‐Oral; Sibel Erkal; Ahmet Sirkecioglu; Djursun Karasartova; Fikret Sahin; Serife Birgül Tan...; Fatma Seniha Güner
• Keywords: Isocyanate; Hexamethylene diisocyanate

Abstract As an alternative to petroleum‐based polyol, hydroxyl containing material was prepared from linseed oil for polyurethane synthesis. Hexamethylene di‐isocyanate (HMDI) and/or 4, 4′‐methylene diphenyl (MDI) were used as isocyanate source. The polymerization reaction carried out without catalyst. Polymer films by casting‐evaporation technique. MDI/HMDI‐based and its had higher T g better thermal property than that of the HMDI‐based one because existence benzene ring in polymer chain. Static water contact angle determined be 74° 77.5° HMDI films, respectively. Water adsorption found around 2.6–3.6% both films. In vitro degradation polyurethanes phosphate buffered saline at 37°C investigated gravimetric method. Fourier transform infrared spectroscopy scanning electron microscopy confirmation on surface. rate film film. Both direct method MMT test applied determination cytotoxicity here not cytotoxic. Silver‐containing using Biocera A® filler screened their antibacterial performance against Escherichia coli, Pseudomonas aeruginosa , Staphylococcus aureus Bacillus subtilis . with exhibited activity. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2010