Differential Distribution of Renal Nerves in the Sympathetic Ganglia of the Rat

• DOI: 10.1002/ar.23680
• Publication Date: 2017-08-17T15:46:40Z
• Authors: Seishi Maeda; Mayumi Fujihira; Yusuke Minato; Sachi Kuwahara‐Otani; Koichi Tanaka; Tetsu Hayakawa; Hideshi Yagi
• Keywords: Retrograde tracing; Anterograde tracing

The renal nerve plexus comprises efferent and afferent fibers. It controls urine production bodily fluid homeostasis. Efferent fibers to the kidney include sympathetic from their main ganglia, prevertebral suprarenal ganglia (SrG), paravertebral chain (ChG). In present study, we examined topological innervation these parenchymal segments of left rat. Fluoro-Gold was injected into rostral or caudal poles kidney. Approximately 50% cells in SrG rats pole were labeled, while 60% ChG T13 labeled. addition, performed dual-probe retrograde tracing nerves using two kinds fluorescent-conjugated cholera toxins (f-CTbs) labeled with each f-CTb distributed differently lower ChGs; no dual-labeled found ganglia. Anterograde pCAGGS-tdTomato vector transfected showed that tdTomato-labeled varicosities extended cortical arterioles urinary tubules. Immunohistochemistry revealed they positive tyrosine hydroxylase synaptophysin, suggesting possessed endings. Our results show may control part innervate multiple effectors cortex. Anat Rec, 300:2263-2272, 2017. © 2017 Wiley Periodicals, Inc.