Population-based study of mortality and major amputation following lower limb revascularization

• DOI: 10.1002/bjs.10823
• Publication Date: 2018-04-25T08:36:46Z
• Authors: K Heikkila; I M Loftus; D C Mitchell; A S Johal; S Waton; D A Cromwell
• Keywords: Cumulative incidence; Intermittent claudication; Claudication

Abstract Background The aim of this study was to estimate separate risks major lower limb amputation and death following revascularization for peripheral artery disease (PAD) using competing analysis. Methods Routinely collected data from Hospital Episode Statistics (HES) were used identify patients who underwent endovascular or open PAD in England 2005 2015. primary outcomes within 5 years revascularization. Cox proportional hazards Fine–Gray regression examine the these outcomes. Results Some 164 845 their first during interval. Most men (64·6 per cent) median age 71 (i.q.r. 62–78) years. Following revascularization, 5-year cumulative incidence 4·2 cent with intermittent claudication 18·0 those a record tissue loss. corresponding rates 10·8 25·3 respectively after 8·1 25·0 combined procedures. varied 24·5 39·8 cent, depending on procedure type. Competing methods consistently produced estimates than standard methods. Conclusion risk appears estimated previously. Patients undergoing loss require an are at highest