Long-term results in patients with T2–3 N0 distal rectal cancer undergoing radiotherapy before transanal endoscopic microsurgery

• DOI: 10.1002/bjs.5178
• Publication Date: 2005-10-27T10:46:36Z
• Authors: E Lezoche; M Guerrieri; A M Paganini; M Baldarelli; A De Sanctis; G Lezoche
• Keywords: Abdominoperineal resection; Radical surgery

Local excision after radiotherapy for node-negative low rectal cancer may be an alternative to radical excision. This study evaluated the results of local in patients with small (less than 3 cm diameter) T2 and T3 distal tumours following neoadjuvant therapy.One hundred (54 uT2 46 uT3 uN0 tumours) were enrolled. All underwent preoperative followed by means transanal endoscopic microsurgery.Definitive histological examination revealed nine pT1, 54 pT2 19 pT3 tumours. A complete response (R0) or microscopic residual tumour (R1mic) was found three 15 respectively. Minor complications occurred 11 major two. At a median follow-up 55 (range 7-120) months, failure rate 5 per cent metastatic disease two patients. The cancer-specific survival at 90 months' 89 cent, overall 72 cent. Salvage abdominoperineal resection performed patients, whom free months.Treatment cancers high-dose microsurgery is acceptable conventional resection.