Investigation of chemical changes in Polygonatum kingianum after traditional processing by multiple fingerprint profiles in combination with multivariate methods

• DOI: 10.1002/bmc.5320
• Publication Date: 2022-01-05T06:04:11Z
• Authors: Jing Wang; Zefei Du; Qingshu Yang; Jianbo Yang; Baozhong Duan
• Keywords: Chemometrics; Hierarchical clustering

Polygonati Rhizoma (Huangjing) is traditional medicine in China, which can only be used as after being processed. However, there a limited theoretical basis for analyzing the changes chemical components processing. In this study, analytical techniques including Fourier transform infrared spectroscopy, high-performance gel permeation chromatography-evaporative light scattering detection, and HPLC-diode array detection were proposed to perform multiple fingerprint analyses of processed materials; total sugar was also determined. Moreover, chemometric studies, hierarchical cluster analysis principal component analysis, visualize discrimination raw materials. The results revealed that constituents had been profoundly changed following sample conclusion, these methods could successfully compare materials Polygonatum kingianum, elaborate rationality processing from perspective composition.