Predictors and outcomes after transcatheter aortic valve implantation using different approaches according to the valve academic research consortium definitions

• DOI: 10.1002/ccd.24751
• Publication Date: 2012-11-21T20:16:17Z
• Authors: Moritz Seiffert; Renate Schnabel; Lenard Conradi; Patrick Diemert; Johannes Schirmer; Dietmar Koschyk; Matthias Linder; Jan F. Kersten; Andrea Grosser; Sandra Wilde; Stefan Blankenberg; Hermann Reichensp...; Stephan Baldus; Hendrik Treede
• Keywords: Aged, 80 and over; Balloon Valvuloplasty; Heart Valve Prosthesis Implantation; Male; Cardiac Catheterization; Patient Selection; Heart Valve Diseases; Myocardial Infarction; Kaplan-Meier Estimate; Acute Kidney Injury; 3. Good health; 03 medical and health sciences; 0302 clinical medicine; Aortic Valve; Germany; Heart Valve Prosthesis; Multivariate Analysis; Humans; Female; Clinical Competence; Learning Curve; Aged; Proportional Hazards Models

Objectives We report the results of a large single‐center study evaluating predictors and outcomes after transcatheter aortic valve implantation (TAVI) with different devices access routes according to Valve Academic Research Consortium (VARC). Background The widespread adoption TAVI warrants systematic analysis outcomes. Only few comprehensive data exist comparing approaches as selected by heart team. Methods was performed in 326 consecutive patients (mean age 80.6 ± 7.1 years, 55.5% female) at high risk for surgery balloon‐expandable self‐expanding through transfemoral or transapical access. Data were analyzed VARC endpoints; mortality identified. Results All‐cause 10.1% (30 days) 29.9% (1 year) overall comparable regard choice ( P = 0.295) despite profiles baseline. Device success 30‐day safety endpoints achieved 87.1 21.2%. Myocardial infarction [hazard ratio (HR) 6.52], stage‐2 −3 acute kidney injury (HR 2.52 6.80) major site complications 1.96) independent 1‐year all‐cause mortality. had protective effect 0.58). Baseline included body mass index <20 kg/m 2 3.20), NYHA class IV 1.87), left ventricular ejection‐fraction <30% 2.30), higher STS‐PROM scores 1.05 per percent), (group 75–85 HR 0.47). Conclusions Comparable team approach. perioperative identified, contributing refinement patient device selection criteria TAVI. © 2012 Wiley Periodicals, Inc.