Complete versus culprit‐only strategy in older MI patients with multivessel disease

• DOI: 10.1002/ccd.30075
• Publication Date: 2022-02-16T10:27:07Z
• Authors: Simone Biscaglia; Andrea Erriquez; Matteo Serenelli; Fabrizio D'Ascenzo; Gaetano De Ferrari; Albert Ariza Sole; Juan Sanchis; Francesco Giannini; Francesco Gallo; Antonella Scala; Alberto Menozzi; Michele Pighi; Raul Moreno; Gianmarco Iannopollo; Mila Menozzi; Vincenzo Guiducci; Matteo Tebaldi; Gianluca Campo
• Keywords: Culprit; Cumulative incidence

The revascularization strategy to pursue in older myocardial infarction (MI) patients with multivessel disease (MVD) is currently unknown. For this reason, while waiting for the results of dedicated trials, we sought compare a complete versus culprit-only MI by merging data from four registries.The inclusion criteria target population present study were (i) age ≥ 75 years; (ii) (STE or NSTE); (iii) MVD; (iv) successful treatment culprit lesion. Propensity scores (PS) derived using logistic regression (backward stepwise selection, p < 0.2). primary outcome was all-cause mortality. Secondary outcomes cardiovascular (CV) death, MI, and major bleeding. Multivariable adjustment included PS inverse probability weighting (IPTW). Kaplan-Meier plots weighted IPT. Among 2087 included, 1362 (65%) received whereas 725 (35%) revascularization. mean 81.5 years, follow-up 419 ± 284 days. Seventy-four (10%) died group 223 one (16%). adjusted cumulative 1-year mortality 9.7% 12.9% (adjusted HR: 0.67, 95% CI: 0.50-0.89). Complete associated lower incidence CV death 0.68, 0.48-0.95) HR 0.48-0.95).Culprit-only default MVD. In our analysis, rate.