Mechanoredox‐Catalyzed Organic Synthesis with Piezoelectric Materials: Quo Vadis?

• DOI: 10.1002/cctc.202401814
• Publication Date: 2025-01-24T13:48:39Z
• Authors: Hanggara Sudrajat; Hsien‐Yi Hsu; François Jérôme; Juan Carlos Colme...
• Keywords: Organic Synthesis

Abstract Piezoelectric materials offer great promise due to their ability generate electric fields under mechanical stress, producing surface charges that drive otherwise kinetically sluggish redox reactions. The strained surfaces of these provide a unique advantage in controlling product selectivity and enabling reaction pathways are unattainable with conventional methods. This perspective highlights advancements, challenges, the future potential piezoelectric synthetic organic chemistry, focus on designing optimized for piezocatalyzed synthesis. Piezocatalysis is industrially relevant because its operational simplicity, mild, gram scale synthesis reusable catalysts, minimal solvent use, air tolerant conditions. It involves cycles facilitate one electron events without requiring light exposure or electrical bias. Despite significant progress, many fundamental aspects yet be fully understood. One example correlation between piezoelectricity catalytic activity, which not always linear, as demonstrated by comparison tetragonal cubic BaTiO₃. While BaTiO₃ piezoelectric, it shows excellent activity certain reactions such arylation, dicarbonylation, cyclization mechanochemical conditions comparable Considering all aspects, this aims stimulate discussion advance promising field right direction.