ChemInform Abstract: Formal [4 + 1]‐ and [5 + 1]‐Annulation by an SN2—Conjugate Addition Sequence: Stereoselective Synthesis of Highly Substituted Carbocycles.

Cyclopentanes Annulation Stereocenter Conjugate Sequence (biology) Formal synthesis Methylene
DOI: 10.1002/chin.201240055 Publication Date: 2012-09-07T14:22:37Z
ABSTRACT
Abstract The reaction of 6‐bromo‐2‐hexenoates with active methylene compounds proceeds via formal [4 + 1]‐annulation and affords highly functionalized cyclopentanes up to 4 stereocenters.
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