ChemInform Abstract: Nucleophilic Substitution of Propargyl Alcohols with Aliphatic Alcohols, Aliphatic Amines and Heterocycles Catalyzed by 4‐Nitrobenzenesulfonic Acid: A Scalable and Metal‐Free Process.

• DOI: 10.1002/chin.201441096
• Publication Date: 2014-09-25T11:35:02Z
• Authors: S. Antony Savarim...; D. G Leo Prakash; S. Augustine Thomas
• Keywords: Tamil; Propargyl

Abstract It is aimed to provide a cost effective p-NBSA catalyzed nucleophilic substitution of propargyl alcohols with alcohols, amines and heterocycles, without employing corrosive and costly metal catalysts, toxic solvents and column chromatography for purification. A systematic study of C C, C N and C O bond formation and efficacy of the scalability have also been confirmed.