ChemInform Abstract: Convenient Method for the Synthesis of Phthalazinones via Carbonylation of 2‐Bromobenzaldehyde Using Co2(CO)8 as a CO Source.

• DOI: 10.1002/chin.201445184
• Publication Date: 2014-10-23T15:04:49Z
• Authors: A. Sivalingam Suresh; Poongavanam Babur...; Mansur Ahmed
• Keywords: 01 natural sciences; 0104 chemical sciences

Abstract A simple one-pot synthesis of phthalazinones by the condensation and intra-molecular carbonylative cyclization of 2-bromobenzaldehydes with hydrazines is reported. This method utilizes solid Co2(CO)8 as carbonyl source making it readily accessible in small-scale laboratory applications.