A Sugar‐Modified Phosphole Gold Complex with Antiproliferative Properties Acting as a Thioredoxin Reductase Inhibitor in MCF‐7 Cells

• DOI: 10.1002/cmdc.200800210
• Publication Date: 2008-08-29T11:21:25Z
• Authors: Elodie Viry; Eric Battaglia; Valérie Deborde; Tobias Müller; Régis Réau; Elisabeth Davioud...; Denyse Bagrel
• Keywords: MCF-7; Phosphole

A phosphine-coordinated gold(I) thiosugar complex was found to exert potent cytotoxic and antiproliferative effects through thioredoxin reductase inhibition in MCF-7 cells.