Synthesis of NH‐Sulfoximines by Using Recyclable Hypervalent Iodine(III) Reagents under Aqueous Micellar Conditions

• DOI: 10.1002/cssc.201903430
• Publication Date: 2020-01-17T09:00:37Z
• Authors: Guocai Zhang; Hongsheng Tan; Weichun Chen; Hong C. Shen; Yue Lu; Changwu Zheng; Hongxi Xu
• Keywords: Hypervalent molecule; Iodine compounds

The synthesis of NH-sulfoximines from sulfides has been first developed under mild conditions in an aqueous solution with surfactant TPGS-750-M as the catalyst at room temperature. In this newly process, a simple and convenient recycling strategy to regenerate indispensable hypervalent iodine(III) is used. resulting 1,2,3-trifluoro-5-iodobezene can be recovered almost quantitively mixture by liquid-liquid extraction then oxidized give corresponding species. This optimized procedure compatible broad range functional groups easily performed on gram scale, providing green protocol for sulfoximines.