Mental health status and related influencing factors of COVID‐19 survivors in Wuhan, China

• DOI: 10.1002/ctm2.52
• Publication Date: 2020-06-08T14:57:39Z
• Authors: Chaomin Wu; Xianglin Hu; Jianxin Song; Dong Yang; Jie Xu; Kebin Cheng; Dechang Chen; Ming Zhong; Jinjun Jiang; Weining Xiong; Ke Lang; Yan Tao; Xiaoqin Lin; Guohua Shi; Liwen Lu; Longci Pan; Lei Xu; Xin Zhou; Yuanlin Song; Ming Wei; Junhua Zheng; Chunling Du
• Keywords: Depression; Pandemic

Dear editor, In late December 2019, a novel contagious pneumonia named coronavirus disease 2019 (COVID-19) has broken out in Wuhan, China.1 On January 30, 2020, World Health Organization (WHO) declared COVID-19 as Public Emergency of International Concern. March 11, WHO characterized pandemic.2, 3 Much research work been done for hospitalized patients, mainly clinical characteristics.4 However, few studies have reported the post-discharge follow-up status, especially mental health status survivors. Therefore, this descriptive case series, we enrolled large number survivors China. We aimed to report these and explore relevant influencing factors. This study was conducted Wuhan Jinyintan Hospital. All patients were confirmedly diagnosed with COVID-19.1 The flowchart is shown Figure S1. Eventually, 370 included study. Verbal consent obtained all Survivors' readmission reasons inquired. Post-discharge respiratory symptoms Whether worried about recurrence infection others (family members) Home quarantine lifestyles Anxiety measured using Generalized Disorder Screener (GAD-7). Total score 0-4 refers no anxiety; total 5-21 anxiety.5 Depression Patient Questionnaire-9 (PHQ-9). depression; 5-27 depression.6 Statistical analysis performed SPSS (Version 24.0). Continuous variables presented by mean ± standard deviation (SD) or median inter quartiles (IQR). Categorical percentage. Student's t-test Chi-square test used appropriate. P < .05 statistically significant. Clinical data summarized Table 1. time from discharge 22 days (IQR 20-30 days). Six (1.6%) readmitted hospital during follow-up, including two cough without SARS-CoV-2 RNA positive, one transient positive pneumonia, lumbar disease. No SARS-CoV-2-positive recurred any follow-up. Sixty (16.2%) had 45 (12.2%) breathlessness after activity. Twenty (5.4%) sputum production One hundred seventy-three (46.8%) 174 (47.0%) others. Two ninety-three (79.2%) took home lifestyle. Fifty (13.5%) occurred anxiety. Forty (10.8%) depression. As S1, (39.2%) most bothered feeling nervous, anxious, on edge. S2, high proportion 29.5% sleeping disorders. Four (1.1%) once thoughts suicide several days. 2, symptoms, worry recurrence, significantly increased incidence anxiety (P .05). Female, others, lifestyle depression not associated age, family infection, comorbidity, so on. study, recurrent population period. identified survivor turning into positive. soon turned negative again (interval: 5 days) just when he readmitted. Chinese experts pointed that equal re-infection.7 There might be survivors: first, it comes nucleic acid fragments inactivated SARS-CoV-2; second, virus titer lowers level can hardly detected at discharge, residual fluctuated but would cleared body immunity. should overly rare event found recurrence. An epidemic disease, such SARS 2003, generally accompanies multiple psychiatric morbidities, anxiety, depression, even suicide.8 our existed approximately 10% also For those severe disorders, some medications could prescribed help them improve sleep. Survivors suicidality must closely followed up cared psychiatrists. are Besides, females more susceptible clinicians explain symptom common recovery period pneumonia. goes by, gradually disappear. national diagnosis treatment scheme COVID-19,9 suggested take 2 weeks. main requirements living single drafty room, reduction close contact family, separate meals, avoidance outdoor conduct necessary avoid unexpected infections effective measures need taken relieve caused lifestyle, online chat video indoor exercise, summary, develop because Female addition, noted relieved. authors conflict interest. supported Special Fund Shanghai Jiaotong University Coronavirus Disease Control Prevention (2020RK47 Dr Junhua Zheng), National Natural Science Foundation China (NSFC) (81630001, 81770075, 81870035, 82041003), Technology Commission Municipality (20411950402, Municipal Key Specialty (shslczdzk02201) Top-Priority Disciplines Construction Project (2017ZZ02013), key discipline medicine (ZK2019B06), municipal commission planning (201740210), Academic Leader Qingpu District Healthcare (WD2019-36), Sub-specialist project Branch Zhongshan Hospital, Fudan university (YZK 2019-04), Hospital-level Incubation (QYP 2019-03), technology development fund district science 2018 (QKY 2018-01). thank Dr. Feng Zhou Juli Wang (Qingpu Branch, Shanghai, China) guidance follow up. support findings available corresponding author upon appropriate request. Please note: publisher responsible content functionality supporting information supplied authors. Any queries (other than missing content) directed article.