Counterfeit analysis strategy illustrated by a case study

• DOI: 10.1002/dta.1908
• Publication Date: 2015-12-22T10:18:41Z
• Authors: Klara Dégardin; Yves Roggo
• Keywords: Profiling (computer programming); Counterfeit Drugs

Medicine counterfeiting is a current problem that the whole pharmaceutical field has to deal with. In 2014, counterfeits entered legitimate supply chain in Europe. Quick and efficient action had be taken. The aim of this paper explain which analytical strategy was chosen with six cases concerned criteria have considered provide quick thorough information about counterfeits. evaluation packaging performed first step, based on comparison genuine samples manipulation signs. Chemical methods were then used, consisting near infrared spectroscopy, capillary zone electrophoresis ultraviolet-visible spectrophotometry, order authenticate chemical composition confirmed Among 20 analyzed, 17 as results samples, one contained totally counterfeited parts. Several signs asserted, like addition glue boxes vials. Genuine stolen goods been diluted water, while for an isolated case, different active ingredient introduced vial. data generated further investigated from forensic intelligence perspective. Links could revealed between analyzed counterfeits, together some interesting modus operandi counterfeiters. study limited number cases, therefore encourages profiling at bigger scale. Copyright © 2015 John Wiley & Sons, Ltd.